Studies on oxidant-antioxidant and trace minerals alteration in equine upper respiratory affection

In equine field, respiratory affections are common diagnostic problems, strangles is a bacterial disease causing airway affection in young horses. This study aimed to evaluate oxidant/antioxidant status in strangles affected horses. Fifteen horses (15) were evaluated in this study, the levels of SOD, GPx, Catalase, MDA, hydrogen peroxide and antioxidant trace minerals (Zn and Cu) were estimated. Significant decrease in SOD, GPx, Zn along with significant increase in MDA and hydrogen peroxide levels were recorded. Oxidative process has been associated with strangles infection in horses leading to oxidant-antioxidant imbalance and its effect extends to associate antioxidant trace minerals, thus, a future thinking of adding antioxidant supplementation to regular treatment regimen may be rewarding.